Can CallSubDelayed3 calls be lost?

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I have an app with an activity and a service. The activity has a sub (in a class) that is called as a result of a button click, or a timer tick or something happening in the service (Bluetooth data received). Under the case I am working on at the moment the Activity is not paused - but under some circumstances could be.

I have been using CallSubDelayed3(...) in all three cases, the parameters specify the reason for the call so the sub can respond to the user, timeout something...

Can CallSubDelayed3 calls be lost?

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